Certain cells, commonly called excitable cells, are unique because of their ability to generate electrical signals. Although several types of excitable cells exist — including neurons, muscle cells, ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill ...

The Nobel Prize in Physiology or Medicine 2026 has been awarded to Deisseroth, Hegemann, and Nagel, for light-gated ion ...

They are literally channels for communication: Pore-forming proteins in living cells, termed ion channels, are embedded in the outer membrane of almost all cell types and play a crucial role in the ...

Tetrameric cation channels are the largest and best characterized group of ion channels. For this type of ion channel, the ion pathway lies in a pore domain consisting of two transmembrane helices ...

Have you ever been studying pharmacology and felt like you couldn't quite visualize where in the body a drug is actually ...

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...