Oxidized lipids—fats structurally altered by enzymes, oxygen or free radicals—are double-edged swords that can both quell and ...

TMEM63B, a mechanosensitive lipid scramblase, has an autoinhibitory domain in its C-terminal tail that helps keep it inactive ...

Lipids are biomolecules essential for the proper functioning of the living cell. They are found in the cell membranes and are also integral components of cell signaling pathways. Plant cells possess ...

Super-resolution imaging and mathematical modelling show that clathrin-mediated endocytosis sorts lipids only weakly, with ...

Weill Cornell Medicine investigators have determined how a molecule within cells can help tune the eyes' sensitivity to light. The study identified the molecule's binding site on a protein in retinal ...

Hepatic lipid homeostasis is critical for both cellular function and overall metabolic health. Disruptions in lipid homeostasis can lead to fatty liver diseases, which have become a significant global ...

The rice blast fungus Magnaporthe oryzae is one of the most destructive plant pathogens on Earth, stripping away roughly six ...

A closer look at the placental lipidome reveals molecular differences between active and inactive pregnancies, offering new ...

Obesity and obesity-associated diseases, such as type 2 diabetes mellitus and cardiovascular diseases, have reached pandemic levels worldwide and are major threats to human life. Lipid species within ...

Precise quantification and annotation of individual lipids is critical for understanding the complicated lipid function in biological systems. But achieving both concurrently is challenging.