The mammalian target of rapamycin complex 1 (mTORC1) kinase regulates cell growth in response to growth factors, energy levels and amino acid availability, and is activated by RHEB, a Ras-related ...
Multiple strategies have been employed by pathogenic bacteria to sabotage host innate immune signaling to facilitate their infection. Previous studies revealed that the Yersinia effector protein YopJ ...
In a new study, researchers from Osaka University discovered a novel molecular mechanism by which immune cells migrate to fight off infections. These findings may help in understanding the development ...
mTORC1 activation requires the coordinated input of amino acid sufficiency and growth factor signaling, operating as an “AND” gate. To ensure both conditions are met, mTORC1 must first translocate to ...
A team of Whitehead Institute scientists has for the first time revealed the molecular structure of a critical growth regulator bound to its partner proteins, creating a fine-grained view of how they ...
The mammalian target of rapamycin complex 1 (mTORC1) kinase regulates cell growth in response to growth factors, energy levels and amino acid availability, and is activated by RHEB, a Ras-related ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results