This new article publication from Acta Pharmaceutica Sinica B, discusses how a CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment ...

In this work, we propose a molecular communication model, CoTiR, with a bio-inspired directional migration strategy (DMS) for guided propagation of exosomes to target the damaged tissues. The model ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Home > Press release: Immune system response to viral ...

An understanding of the human innate immune response is essential to accelerate the progress and clinical trials of drugs and antibiotics. This requires efficient modelling of the molecular network. A ...

Establishing stimulus-responsive nanosystems for the codelivery of anticancer drug and oligonucleotide is a promising strategy in cancer treatment owing to the combination of chemotherapy and gene ...

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine ...

Cold weather triggers brown fat to burn energy, thanks to a newly discovered protein switch. This natural calorie-burning ...

Bulk-Phase Model Preparation The three-dimensional amorphous systems were constructed with the molecular models of HB-PEI or HB-PPI in a simulation box of 40 × 40 × 40 Å 3, with periodic boundary ...

A collaborative study from the University of Cologne has uncovered how a key mitochondrial protein, AIFM1 (Apoptosis-Inducing ...

Background: Heatstroke (HS) is becoming more concerning, with coagulopathy contributing to higher mortality. The aim of this study was to analyze the metabolomic and proteomic profiles associated with ...