Researchers have created an array of nanopillars that can breach the nucleus of a cell -- the compartment that houses our DNA -- without damaging the cell's outer membrane. This new 'gateway into the ...
For decades, biologists assumed a cell's energy simply diffused to wherever it was needed. It turns out the most important destination of all has a private delivery line. Subscribe to our newsletter ...
Direct interactions between the cell’s powerhouses and nuclear pores might channel energy straight into the nucleus, fuelling cell division and differentiation. Menendez-Montes et al. investigated ...
The cell nucleus goes a long way during an immune response, both literally and figuratively. New research published in Science Immunology shows that in some white blood cells, this genetic storage ...
An international study led by the University of Basel has discovered that nuclear pore complexes—tiny gateways in the nuclear membrane—are not rigid or gel-like as once thought. Their interiors are ...
Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...
Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...
A team of researchers at Åbo Akademi University in Finland made a surprising discovery. They found that Talin-1, a protein primarily known for its role in cell adhesion at the periphery of the cell, ...
Aging progressively affects how our bodies function. Among other effects, it reduces the ability of the hematopoietic system—the organs and tissues responsible for producing blood cells—to maintain ...
A PLOS Genetics study shows that destabilizing chromatin through a histone H3 mutation hyperactivates the nutrient-sensing ...
ChromAgeNet has decoded chromatin architecture, the 3D organisation of DNA in the nucleus, distinguishing young from aged blood stem cells and opening new paths for cell rejuvenation. View on euronews ...