Wyle recently reunited with fellow ER alums Julianna Margulies and Anthony Edwards, who played Carol Hathaway and Mark Green, at the opening night of Clooney's Broadway play Good Night, and Good Luck on April 3.

Clooney and Wyle, who played Doug Ross and John Carter, respectively, starred alongside each other on the hit medical drama for five seasons before Clooney exited the series to focus on other acting endeavors. Wyle continued with the show through season 11, making guest appearances in seasons 12 and 15. ER ran from 1994 to 2009.