The Food and Drug Administration has approved the first-ever stand-alone nasal spray to treat drug-resistant depression.

Jules Feiffer, the cartoonist and playwright whose syndicated comic strip ran for four decades, has died. The Pulitzer Prize and Tony Award winner was 95.

He found his voice in comics that provided a sardonic and sarcastic takedown of authority and conventional wisdom. He was also a playwright and screenwriter.

Although depression most often arises in response to some kind of defeat, depression can seem to arise out of the blue, for no obvious reason. It may even arise when life appears to be going ...