Israel launched a major military operation Tuesday in the occupied West Bank city of Jenin that killed at least nine Palestinians and left at least 40 more people wounded, Palestinian health officials said,

Israel’s military is using lessons from the Gaza war in its new West Bank operation to ensure “terrorism does not return,” according to Defense Minister Israel Katz.

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As many as 600 people were held in a hospital overnight, the mayor of the city of Jenin told a Palestinian news agency. The death toll from the two-day operation rose to 10, officials said.

The operation follows Israeli concerns about the presence of Iran-backed groups in the Palestinian territory as well as a crackdown by the Palestinian Authority's security services.

Prime Minister Benjamin Netanyahu said the assault on Jenin would be “extensive and significant,” as the military erected new checkpoints across the West Bank.

The Israeli military killed at least seven Palestinians in the occupied West Bank on Tuesday as the prime minister announced the start of a “large-scale military operation” in the restive city of Jenin.

The Israeli military launched a large raid in the city of Jenin in the occupied West Bank on Tuesday, killing nine people and injuring 40 others, according to Palestinian health officials.